delete https://{baseUrl}/V1/storeview//user/quote/item/
Remove item from quote using the item_id (each item after being added to the quote will get a unique id for that quote).
Sample Curl
curl --location --request DELETE 'https://mygatewayurl.com/V1/storeview/default/user/quote/item/10' --header 'Authorization: Bearer qsk2p2azmuylkcgsuhhkbale7vk571vn'